Contraindications of the most important drugs
Atropine :
- Benign prostatic hyperplasia ( Senile prostate )
- Closed-angle glaucoma
Oral contraceptives :
- Cerebrovascular disease
- Thromboembolism
- Estrogen-dependent neoplasm
- Liver disease
- Pregnancy
Reserpine :
- Depression
- Peptic ulcer
- Parkinsonism
Aspirin :
- Pregnancy and breast-feeding woman
- Gout
- Chronic kidney disease
- During surgery
Sulphonamides :
- Pregnancy
- In newborns and infants less than two months of age
Captopril :
- Pregnancy
- Severe renal failure
- Bilateral renal artery stenosis
- Angioedema
Morphine :
- Head injury
- Increased intracranial tension
- Epilepsy
- Respiratory diseases : Asthma and chronic obstructive pulmonary disease
- Pregnancy and labor
- Liver disease
- Myxedema
- Biliary and renal colic
Verapamil :
- Congestive heart failure
- Atrioventricular block
Warfarin :
- Pregnancy and labor
- Bleeding states
- Vitamin K deficiency
- Liver disease
Amitriptyline :
- Bipolar disorder
- Unstable angina
- Benign prostatic hyperplasia
- Epilepsy
- Preexisting arrhythmia
Chloramphenicol :
- In patients with G6PD deficiency
- Liver diseases
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) :
- Liver disease
- Pregnancy and breast-feeding woman
- Chronic renal insuffeciency
- Severe heart disease
- Hypovolemia
Corticosteroids :
- In patients taking protease inhibitor
- Hypocalcemia and vitamin D deficiency
- Hyperglycemia
- Hypokalemia
- Liver diseases
Adrenaline :
- CVS disease : Hypertension, angina and arrhythmia.
- Thyrotoxicosis
- Pulmonary embolism
- Around finger and toe with local anesthetics
Ofloxacin :
- Patients predisposed to arrhythmia or taking anti-arrhythmic medication
- Chronic renal disease
Propranolol :
- CVS diseases : Heart block, sever heart failure, hypotension and variant angina.
- Peripheral vascular disease
- Bronchial asthma
- Uncontrolled diabetes mellitus
Furosemide :
- Electrolyte imbalance > Hyponatremia, hypokalemia, hypochloremic alkalosis and hypotension.
- Liver failure with impaired consciousness
- Hypersensitivity to furosemide
Heparin :
- Bleeding disorders
- Hypersensitivity to heparin
- Surgery of the brain, eye or spinal cord.
Thiazide Diuretics :
- Hypersensitivity to thiazide
- In patients taking digoxin
- Uncontrolled diabetes mellitus
Tetracycline :
- Renal impairment
- Pregnancy and breast-feeding women
- Children less than 8 years of age
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