Complications of some common diseases - part 1
Bronchiectasis :
( General complications )
- Systemic pyemia
 - Secondary amyloidosis
 
( Local complications )
- Lung abscess and gangrene
 - Suppurative Pericarditis
 - Empyemia and pyopneumothorax
 - Pulmonary fibrosis and right-sided heart failure
 - Bronchogenic carcinoma
 
Portal hypertension :
- Esophageal varices and its hemorrhage and rupture
 - Blood vessels congestion
 - Gastrointestinal bleeding
 - Ascites
 - Enlarged spleen
 - Vomiting blood
 
Peptic ulcer :
- Haemorrhage in the form of haematemesis and melaena
 - Perforation leading to septic peritonitis
 - Healing by fibrosis leading to pyloric stenosis ( if the ulcer is in the pyloric region) or hour-glass stomach ( if the ulcer is in the lesser curvature)
 - Malignant change : occurs in 1% of peptic ulcers.
 
Systemic hypertension :
- Left ventricular failure and coronary atheroma
 - Cerebral hemorrhage and hypertensive encephalopathy
 - Benign and malignant nephrosclerosis
 - Retinal exudation and hemorrhage
 
Liver cirrhosis :
- Portal hypertension
 - Splenomegaly
 - Liver cell failure : leading to gynecomastia and malignant change
 - Ascites
 
Lobar pneumonia :
- Lung abscess and gangrene
 - Pericarditis and empyemia > Direct spread
 - Septicemia > Blood spread
 - Carnification : Pulmonary fibrosis
 - Meningitis, peritonitis and pleuritis.
 - Adult respiratory distress syndrome
 
Gall bladder stones :
- Biliary colic
 - Acute cholangitis
 - Acute and chronic cholecystitis
 - Acute biliary panceriatits
 - Obstructive jaundice ( Cholestasis )
 - Carcinoma of gall bladder
 - Acute intestinal obstruction
 
Sudden coronary artery occlusion :
- Myocardial infarction
 - Ventricular fibrillation
 - Cardiogenic shock
 - Acute heart failure
 - Sudden death
 
Meningococcal meningitis :
- Healing by organisation : leading to adhesions and obstruction followed by hydrocephalus.
 - Meningococcal septicemia leading to acute infective endocarditis.
 - Haemorrhage and necrosis of adrenal cortex
 
Diabetes mellitus :
- Metabolic : Ketosis and diabetic coma.
 - Renal : Pyelonephritis, necrosis of renal papillae, diabetic glomerulosclerosis and nephrotic syndrome.
 - Vascular : Atherosclerosis, myocardial infarction and dry gangrene of the limbs.
 - Infections :
 - Lung : Tuberculosis, lung abscess and gangrene.
 - Skin : Carbuncle
 - Kidney : Pyelonephritis
 
Atherosclerosis :
- Fusiform aneurysm of the abdominal aorta
 - Gradual or sudden ischemia due to thrombus on top of atherosclerosis
 - Thrombosis in the aorta leading to embolism
 - Dissecting aneurysm of the aorta
 
Venous thrombosis :
- Haemorrhage
 - Thrombosis and embolism
 - Trophic changes as varicose ulcers
 - Infection as thrombophlebitis
 
Viral hepatitis :
- Chronic hepatitis : chronic persistent or active hepatitis
 - Fulminant hepatitis : leading to hepatic failure
 - Arthritis-like problems
 
Tumors of placenta :
- Uterine bleeding
 - Benign > Malignant change into choriocarcinoma
 - Malignant > Direct spread and blood spread to lungs
 
Rheumatic fever :
- Pericardial adhesions
 - Myocardial fibrosis
 - Valvular lesions : Stenosis and incompetence
 - Sub acute infective endocarditis.
 
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